Alhemmali et al-August-2015 | Direct Research Center

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Direct Research Journal of Agriculture and Food Science (DRJAFS) Vol.3 (8), pp. 162-166, August 2015
ISSN: 2354-4147

Effects of sub-lethal concentrations Diazinon on some physiological parameters of liver and kidney in the African catfish
Article Number: DRJA17085307
DOI:

Original Research Article

*¹Esmail Mohamed Alhemmali, ²Fathi Alhashmi Bashir, ³Nasreddin Rajab Rhouma and ⁴Aldukali Abdulsalam Alkeskas

¹Zoology Department, Faculty of Science, Misurata University, Misurata, Libya.

²Animal Production Department, Veterinary and Agriculture Sciences Faculty, Al-zawia University, Al-zawia, Libya.

³Microbiology Department, Faculty of Science, Misurata University, Misurata, Libya.

⁴General Department, Faculty of Nursing, Misurata University, Misurata, Libya.

Received: July 13, 2015 Accepted: July 27, 2015 Published: August 11, 2015

Abstract

The present study was undertaken to evaluate the influence of Diazinon on some enzyme active alkaline phosphatase (ALP), aspirate aminotransferase (AST) and alkaline phosphatase (ALT) in liver and levels urea and creatinine in kidney of African catfish (Clarias gariepinus). After exposure to deferent concentrations of Diazinon the LC₅₀ values was 11.76 mg L^-1 at 96 h for Clarias gariepinus. The results showed that long-term exposure to sub-lethel concentrations of Diazinon (1.1 mgL^-1 and 3.3 mgL^-1) were highly significant (P<0.05) in all periods for (ALP), (AST) and (ALT) in liver and both of Urea and creatinine in kidney.All parameters were statistically significant when vitamin C and vitamin E plus Diazinon treated group compared with Diazinon-treated group (P<0.05).

Key words: Kidney, Liver, Enzyme, catfish