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Direct Research Journals
Direct Research Journal of Agriculture and Food Science (DRJAFS) Vol.3 (8), pp. 162-166, August 2015
ISSN: 2354-4147

Effects of sub-lethal concentrations Diazinon on some physiological parameters of liver and kidney in the African catfish
Article Number: DRJA17085307

Original Research Article

*1Esmail Mohamed Alhemmali, 2Fathi Alhashmi Bashir, 3Nasreddin Rajab Rhouma and 4Aldukali Abdulsalam Alkeskas

1Zoology Department, Faculty of Science, Misurata University, Misurata, Libya.

2Animal Production Department, Veterinary and Agriculture Sciences Faculty, Al-zawia University, Al-zawia, Libya.

3Microbiology Department, Faculty of Science, Misurata University, Misurata, Libya.

 4General Department, Faculty of Nursing, Misurata University, Misurata, Libya.

date Received: July 13, 2015     date Accepted: July 27, 2015     date Published: August 11, 2015


The present study was undertaken to evaluate the influence of Diazinon on some enzyme active alkaline phosphatase (ALP),  aspirate aminotransferase (AST) and alkaline phosphatase (ALT) in liver and levels urea and creatinine in kidney of African catfish (Clarias gariepinus). After exposure to deferent concentrations of Diazinon the LC50 values was 11.76 mg L-1 at 96 h for Clarias gariepinus. The results showed that long-term exposure to sub-lethel concentrations of Diazinon (1.1 mgL-1 and 3.3 mgL-1) were highly significant (P<0.05) in all periods for (ALP), (AST) and (ALT) in liver and both of Urea and creatinine in kidney.All parameters were statistically significant when vitamin C and vitamin E plus Diazinon treated group compared with Diazinon-treated group (P<0.05).

Key words: Kidney, Liver, Enzyme, catfish