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Direct Research Journals
Direct Research Journal of Health and Pharmacology (DRJHP):Vol.5 (3), pp. 33-38, December 2017
ISSN 2449-0814

Antibacterial activity, phytochemical properties and mineral content of “Aju Mbaise” decoction administered to nursing mothers
Article Number: DRJA33210569
DOI: https://doi.org/10.26765/DRJHP.2017.0569

Original Research Article


Ezejindu C. N.* and Iro O. K.


Department of Public Health, Faculty of Health Sciences ( Clinical Medicine ) College of Medical and Health Sciences, Abia State University, Uturu, Abia State, Nigeria.

*Corresponding author E-mail: ezejinducosmas@gmail.com.


date Received: November 10, 2017     date Accepted: December 29, 2018     date Published: December 31, 2017

Abstract

This study was conducted to evaluate the phytochemical properties, mineral composition and antibacterial activity of “Aju Mbaise” plant decoction. The objectives are as follows; To extracts and concentrate the active principles in the plants using hot water, To investigate the antibacterial activity of the extracts of the plants (“Aju Mbaise”) against some clinical pathogens, To determine the phytochemical constituent of the plants, To determine the mineral content of the extract/decoction. The antibacterial activity was determined using the discs diffusion method with Salmonella spp, Staphylococcus aureus and Escherichia coli as test isolates. The mineral content was determined using atomic absorption spectrophotometer while the phytochemical analysis was conducted using standard analytical methods. The result of the phytochemical screening showed that “Aju Mbaise” contained appreciable amount of metabolites: alkaloids (6.343%), tannins (3.240%), flavonoids (0.366%), cyanogenic glycoside (0.068%), and saponin (7.600%). While mineral element analysis showed that the decoction contained high level of potassium (130.30 mg/ml),calcium(12.43 mg/ml), magnesium (10.40 mg/m) and sodium(4.60mg/ml) and low levels of iron (2.15 mg/ml), zinc (2.23 mg/ml), phosphorus (0.80 mg/ml), copper (0.07 mg/ml), manganese(0.05 mg/ml) and chromium (0.06 mg/ml). The antibacterial screening revealed that the decoction inhibited the growth of gram negative bacterial with the maximum inhibition observed against E. coli (9.0 mm ), followed by Salmomellas pp (8.5 mm) and the minimum inhibition observed against E. Coli (7.5mm) and Salmonella spp (6.5 mm) while the gram positive bacterium (Staphylococcus aureus) was resistant to the decoction. These results suggest that, the decoction of “Aju mbaise” plants contains active principles which are responsible for their antibacterial activities and this provides the basis for their folkloric use as cure for various human ailments.


Keywords: Antibacterial activity, Phytochemical, Decoction, Nursing mothers.