Original Research Article
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Article Number: DRJCMS281006153
DOI: https://doi.org/10.26765/DRJCMS281006153
ISSN: 2354-4163
Vol. 11(6), Pp. 40-48, June 2023
Copyright © 2023
Author(s) retain the copyright of this article
Abstract
Due to the high expense of synthetic medications, pharmaceutical corporations have prioritized research into new chemicals of plant origin for the treatment of ailments. Products made from organic sources are inexpensive and valuable as precursors in the manufacture of medications. Numerous fruits and seeds are recognized to have long-term environmental impacts and to be physiologically active in people. The chemical makeup and biological activity of fruit and seed extracts from Aratocarpus heterophyllus were compared in this study. The research looks at the fruit and seed of the hexanolic extracts of the study sample under inquiry, as well as the proximate analysis, phytochemical screening, mineral content, and bioactivity tests. With the exception of catechin (38.326), ribalinidine (10.593), and epihedrine (42.943), which were present in the fruit but absent from the seed, and cyanogenic glycoside (27.536), lunamarin (0.280), and flavan-3-ol (4.120), which were present in the seed but absent from the fruit, the study demonstrates that the fruit and seed are both rich in nutrients and contain the same phytochemicals. The fruit and seed both contained phytate (33.753 in the fruit and 29.860 in the seed), as well as the secondary metabolite oxalate (37.260 in the fruit and 36.876 in the seed). The results also showed that Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella enterica, Citobactermurliniae, Bacillus licheriformis, Micrococcus roseus, and Bacillus subtilis were sensitive to both the fruit and seed extracts, but ampiclox, the control drug, was less active on the chosen clinical pathogens. For both the fruit and the seed samples, it was discovered that the sample under examination had a high percentage of carbohydrates (52.8 and 51.009, respectively). The fruit has a high mineral concentration, according to the study. According to the study’s findings, fruit and seeds contain active metabolites that have significant therapeutic benefits and are crucial to the pharmaceutical sectors.
Keywords: Aratocarpus heterophyllus fruit, seed, chemical makeupReceived: May 27, 2023 Accepted: June 24, 2023 Published: July 10, 2023