Effects of sub-lethal concentrations Diazinon on some physiological parameters of liver and kidney in the African catfish

Abstract

The present study was undertaken to evaluate the influence of Diazinon on some enzyme active alkaline phosphatase (ALP),  aspirate aminotransferase (AST) and alkaline phosphatase (ALT) in liver and levels urea and creatinine in kidney of African catfish (Clarias gariepinus). After exposure to deferent concentrations of Diazinon the LC₅₀ values was 11.76 mg L^-1 at 96 h for Clarias gariepinus. The results showed that long-term exposure to sub-lethel concentrations of Diazinon (1.1 mgL^-1 and 3.3 mgL^-1) were highly significant (P<0.05) in all periods for (ALP), (AST) and (ALT) in liver and both of Urea and creatinine in kidney.All parameters were statistically significant when vitamin C and vitamin E plus Diazinon treated group compared with Diazinon-treated group (P<0.05).