Article Number: DRJA17085307
ISSN: 2354-4147

Vol.3 (8), pp. 162-166, August 2015

Copyright © 2015
Author(s) retain the copyright of this article

Original Research Article

Effects of sub-lethal concentrations Diazinon on some physiological parameters of liver and kidney in the African catfish

*1Esmail Mohamed Alhemmali

2Fathi Alhashmi Bashir

3Nasreddin Rajab Rhouma

4Aldukali Abdulsalam Alkeskas


The present study was undertaken to evaluate the influence of Diazinon on some enzyme active alkaline phosphatase (ALP),  aspirate aminotransferase (AST) and alkaline phosphatase (ALT) in liver and levels urea and creatinine in kidney of African catfish (Clarias gariepinus). After exposure to deferent concentrations of Diazinon the LC50 values was 11.76 mg L-1 at 96 h for Clarias gariepinus. The results showed that long-term exposure to sub-lethel concentrations of Diazinon (1.1 mgL-1 and 3.3 mgL-1) were highly significant (P<0.05) in all periods for (ALP), (AST) and (ALT) in liver and both of Urea and creatinine in kidney.All parameters were statistically significant when vitamin C and vitamin E plus Diazinon treated group compared with Diazinon-treated group (P<0.05).

Key words: Kidney, Liver, Enzyme, catfish


 Received: July 13, 2015  Accepted: July 27, 2015  Published: August 11, 2015

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