Original Research Article
Isolation and Characterization of Tyrosol from the Stem Bark of Gmelina arborea and its Antimicrobial Activities
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Article Number: DRJCMS008947325
DOI: https://doi.org/10.26765/DRJCMS008947325
ISSN: 2354-4163
Vol. 7(3), Pp. 37-41, December 2020
Copyright © 2020
Author(s) retain the copyright of this article
This article is published under the terms of the
Creative Commons Attribution License 4.0.
Abstract
The purpose of this study was to isolate and characterize the bioactive constituents of Gmelina arborea stem bark using a spectroscopic method (NMR). The crude extract was separated using silica gel column chromatography with a hexane/ethylacetate solvent system. Different fractions were obtained from column chromatography, but fraction G12 showed significant peaks on the spectra that were characteristic peaks of tyrosol when compared to the compound’s literature values. The isolated compound demonstrated high sensitivity to some of the clinical pathogens tested in the study.
Keywords: Steam back, Tyrosol gmelina arorea, antimicropial activitiesReceived: November 6, 2020 Accepted: December 20, 2020 Published: November 28, 2020