Antibiotic Susceptibility of Bacterial Isolates from Post and Non Operative Wound Sepsis in Patients attending Federal Medical Centre Keffi

Abstract

It is a known fact that wound sepsis in rural areas than in cities due to general lifestyle. Thus, this research was to establish likely bacterial isolates from post and non operative wound sepsis in patients attending Federal Medical Centre Keffi and to ascertain the susceptibility of such isolates to conventional antimicrobials and some newly developed ones. A total of 100 swab samples were aseptically collected from post and non operative wound septic patients. Investigations were based on cultural, microscopic identification and characterization of bacterial isolates. Staphylococcus aureus had the highest percentage frequency of 44(58.67%), Pseudomonas aeruginosa 20(26.67%) while Escherichia coli recorded 11(14.67%) (S.aureus > P. aeroginosa > E.coli). Male patients accounted for 53(77.94%) infection rate while female patients accounted for 15(22.06%). S. aureus was most susceptible to cloxacillin (52.27%) than other antibiotics used. Ciprofloxacin exhibited highest efficacy (65.00%) against P. aeruginosa while E. coli showed most susceptibility (30%) to cloxacillin among the antibiotics tested. High occurrence of S.aureus could be linked to the fact that it is a commensal of the skin as opposed to P. aeruginosa and E. coli. Males were affected than females probably because they are being exposed to farm work, fishing and other hazardous activities than their counterparts. For effective antibiotic theraphy, the etiologic agent involved in a particular wound sepsis should be determined and antibiogram conducted on the identified bacterial agent to reduce emergence of multidrug resistant phenomenon.